Best Video Format for PowerPoint 2013/2016 in Windows This article will illustrate the frequently asked question in 5 parts. But on Windows 8 and Windows 10, now you can play MP4 natively as WMV. Prior to Windows 8, MP4 is not a native playback format. What is the best video format for PowerPoint? The answer to this question can be varied depending on what version of PowerPoint and what computer system you are using. If you use PowerPoint in both Mac and Windows and you need to play your presentation in both your Mac or Windows computer, what is the best video format for PowerPoint playable in both PC and Mac? And you need to send PowerPoint presentation file to others but you don’t know if the recipient. Best Video Format for PowerPoint in PC and Mac.